Research at Airedale
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Research at Airedale
The Airedale Research Development and Innovation Team engages in research across a whole range of specialties.
We aim to offer as many patients as possible the opportunity to be part of a research study and support them and their families throughout the whole of their research and treatment journeys.
Ageing
No studies currently recruiting patients.
Anaesthesia, Perioperative and Pain Management
No studies currently recruiting patients.
Cancer
Tracking mutations in cell free tumour DNA to predict Relapse in Early Colorectal Cancer Part C (TRACC C)
Oncological Outcomes after Clinical Complete Response in Patients with Rectal Cancer (OnCore)
Personalising neo-adjuvant Chemotherapy in Locally advanced but operable colon cancer. A randomised trial programme. (FOxTROT)
Axillary management in T1‐3N1M0 breast cancer patients with FNA or core biopsy proven nodal metastases at presentation who convert to node negative after NEoadjuvant Chemotherapy (ATNEC)
A randomised open-label phase III trial of Reduced Frequency pembrolizumab immuNothErapy for first-line treatment of patients with advanced non-small cell lung cancer (NSCLC) utilising a novel multi-arm frequency-response optimisation design (REFINE-Lung)
The HER2-RADiCAL study (Response ADaptive CAre pLan) – Tailoring treatment for HER2 positive early breast cancer (HER2 RADiCAL)
Cardiovascular
CROSS sectional versus invasive imaging in patients with Heart Failure (CROSS-HF)
A Randomised Controlled Trial of Early valve replacement in severe ASYmptomatic Aortic Stenosis (EASY-AS)
Critical Care
Genetics of susceptibility and mortality in critical care (GenOMICC)
Diabetes
DRN 552 (Incident and high risk type 1 diabetes cohort – ADDRESS-2)
Gastroenterology and Hepatology
The UK Inflammatory Bowel Disease Bioresource: Progressing from Genetics to Function and Clinical Translation in Crohn’s Disease & Ulcerative Colitis (IBD Bioresource)
Goals, Needs and outcome Determinants Of Multimodal therapy in Perianal Crohn’s fistula (GONDOMAR)
Endoscopic severity image recognition to advance research and training in Inflammatory Bowel Disease (EVEREST-IBD)
A UK Collaborative Study to Determine the Genetic Basis of Primary Sclerosing Cholangitis (UK-PSC)
Investigation of the Genetic and Molecular Pathogenesis of Primary Biliary Cirrhosis (PBC Genetics)
Barrett’s oESophagus Trial 4: A Randomised Control Trial Comparing capsule sponge Test Screening to Usual Care (BEST4 Screening)
PAN Alimentary Cancer Exhaled breath Analysis (PANACEA)
Haematology
United Kingdom Adult Idiopathic Thrombocytopenic Purpura (ITP) Registry: An Investigation of Disease Progression, Treatment Effectiveness, and Co-morbid Conditions (ITP Registry)
A prospective long-term observational study in patients with monoclonal gammopathy of undetermined significance (SECURE)
A real-world data and sample compendium of frail and/or multiply treated large B-cell lymphoma (ALMANAC)
Musculoskeletal and Orthopaedics
Clinical and immunogenetic characterization of Giant Cell Arteritis (GCA) and polymyalgia rheumatica (PMR) (GCA Consortium)
Prospective observational study of the long term hazards of biologic therapy in rheumatoid arthritis (BSRBR-RA)
Development of a Pan UK Vasculitis Cohort to Analyse Variations in Disease Susceptibility and Outcomes (UKIVAS)
The British Society for Rheumatology Psoriatic Arthritis Register (BSR-PsA)
Reverse or Anatomical replacement for Painful Shoulder Osteoarthritis – Differences between Interventions (RAPSODI-UK)
Investigation of Factors Influencing Psoriatic Arthritis and Psoriasis Response to Therapy with Biologic Drugs (OUTPASS)
Randomised Evaluation of rehabilitation and Acute proximal Humerus fracture: to compare the clinical and cost-effectiveness of a self-directed rehabilitation programme versus physiotherapist-supervised rehabilitation (usual care) for adults with a proximal humerus fracture (REACH)
Rare and Undiagnosed Diseases Study (RUDY)
Fix Or Replace Enhancing distal humeruS fracTure outcomes (FOREST)
The clinical and cost effectiveness of oraL vErsus intrAmuscular glucocorticoiDs in rhEumatoid aRthritis (LEADER)
Development and evaluation of the Digital-My Arm Pain Programme for improving painful distal upper limb musculoskeletal disorders (D-MAPP)
Neurology
Parkinson’s and Movement Disorders Families Project (PFP)
Biology of Juvenile Myoclonic Epilepsy (BIOJUME)
UK MS Register
Renal
National Studies of Rare Kidney Diseases (RADAR)
Reproductive Health and Childbirth
Mothers working to prevent early stillbirth study (MiNESS 20-28)
A phase III, multi-centre, randomised placebo-controlled trial of oral iron supplementation for the prevention of maternal anaemia (PANDA)
Patient reported outcomes for menopause management interventions study (PROMMIS)
Preterm Clinical Network Cohort Research Programme (PCN-CRP) v.1
Respiratory
No studies currently recruiting patients.
Surgery
A randomised controlled trial of minimally invasive surgical treatments for bladder outlet obstruction due to enlarged prostate in the NHS (PREMISE)
Trauma and Emergency Care
Intramuscular tranexamic acid for the treatment of symptomatic mild traumatic brain injury in older adults (CRASH4)
Distal Radius Acute Fracture Trial 3 – Cast versus Splint (DRAFT 3)
Mixed methods study to understand the scale, impact and care trajectory for patients who have a long lie after a fall (LONG-LIE)
Treatment of Toddlers Fractures: Observation Or Immobilisation (TOTs)
Our Research News
Coffee morning celebration for research participants
Tune In: The Story Behind the RAPSODI Study

